The Center for Veterinary Medicine would like pet owners to know that Evamist (estradiol transdermal spray), a topical hormone replacement product, sprayed on the forearm to reduce hot flashes in women during menopause, has the potential to cause health problems in pets exposed to the product on the owner’s skin.
Since Evamist’s approval in 2007, FDA’s Center for Veterinary Medicine (CVM) has received reports of dogs experiencing mammary, or nipple, enlargement and vulvar, (external genital) swelling. In one case the dog experienced liver failure and vaginal prolapse and in the other case the dog had elevated estrogen levels.
In reported cases, the owners had been applying Evamist spray to their forearms. Secondary exposure to the pets likely occurred when the dogs licked the owner’s arms, or while the dog was held by the owner. Small pets (dog, cat, pocket pet) may be especially sensitive to the estrogen in Evamist. Read the entire article.
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